BASIC INTERWIEW QUESTIONS FOR CHEMISTRY STUDENT'S

 

BASIC INTERWIEW QUESTIONS

ORGANIC QUESTIONS

1.What is Boiling Point ?

 It is a temperature of liquid at which the vapour pressure of the liquid is equal to atmospheric pressure.

2.Distinguish between organic compound and inorganic compound.

A compound contain carbon atom is called organic compound either it’s called inorganic compound.

3.how to identify compound aromatic or aliphatic compound ?

 If it burns with sooty flame, it may be aromatic.

On the other hand if it burns with non-sooty flame, it may be aliphatic.

4.Full Form of EDTA

Ethylenediamine tetraacetic acid

5. Full form of NMR

Nuclear magnetic resonance

6.Which metal is found in our blood ?

 Fe(iron)

7.Name the gas which is highly in responsible for greenhouse effect

Carbon dioxide

8.Which acid is present in vinegar ?

 Acetic acid

9.Soap is prepared by boiling caustic soda with.

Fats

10.PVC is obtained by polymerization of..

 Vinyle chloride –(CH2-CHCI)-n

11.Vulcanization of rubber is carried out adding

Sulphur

12.Which gas filled in refrigerator ?

Chlorofluorocarbon

13.Which acid is present in lemon ?

Citric acid

14.What is used to avoid melting of ice ?

 Gelatine

15.Organic compounds are only soluble in ?

 Non polar solvents

16.Carbon occure in nature in the purest form as..

 Diamond

17.Which organic compounds synthesized first in aboratory ?

Urea

18.Which acid is present in “ bee sting” ?

 Methanoic acid (formic acid)

19.Biogas mainly contains ?

Methane

20.Chemical name of Aspirin is

Acetyl salicylic acid

21.Nail polish remover contains which chemical ?

Acetone

22.Trimethylamine Is A Pyramidal Molecule. What Is The Hybridization At Nitrogen?

The nitrogen is bonded to three CH3 groups and has a lone pair, so the hybridisation is sp3.

23.How Many Stereoisomers Of Phenylpropylene Oxide Are There?

Two positional isomer A and B & two Stereoisomer of each so, total 4 isomers.

 24.Which One Of The Following Is Not Aromatic? 1)cyclotetrane 2)benzene 3)napthalene 4)anthracene ?

cyclotetrane, because of the double bonds are not conjugation

 25.Number Of Sigma Bonds Present In Benzene Are Same As ..?

Number of Sigma bonds present in Benzene are same as Borazine (inorganic Benzene).

no. of sigma bonds in Benzene= 12 (C6H6)

no. of sigma bonds in Borazine= 12 (B3N3H6)

26.The Name Benzene Was Proposed By?

Kekule

27.Which Is Useful In The Manufacture Of Insectisides?

Rotenone, Azadirachtin are natural insecticides, synthetic routes are deveoped recently.

DDT, Gammaxene were used but were scraped out as they pose health hazards and are insects are able sustain the max. dosages every year. Generally, Semio-chemicals, a class of compounds found in insects themselves are being studied and used as effective insecticides and warfare agents.

 28.What Are The 4 Classes Of Unsaturated Fatty Acids?

Monounsaturated fat: This is a type of fat found in a variety of foods and oils.

Polyunsaturated fat: This is a type of fat found in plant-based foods and oils.They can be divided into two groups known as omega-3 fats and omega-6 fats. 

Omega-3 fatty acids: One type of polyunsaturated fat made up of mainly omega-3 fatty acids and may be beneficial to heart.

Omega-6 fats decrease risk of heart disease when they are consumed in place of saturated and trans fats.

 29.What Is The Difference Between Coordinate Covalent Bond And Covalent Bond?

IN coordinate covalent bond electrons which are shared by both the atoms are comtributed by only one atom . This is otherwise known as dative bond. 

In covalent bond the electrons shared by both the atoms are contributed by both the atoms equally.

 30.What Happens When Aminoacids React With Alcohols?

when alcohols reats with aminoacids esters are formed. The esters are volatile in contrast to free aminoacids.

R-CH-COOH + H2O-C2H5 -> R-CH-COO-C2H5 + H2O

NH2 NH2

31.What Are Ligases?which Type Of Reactions They Will Catalyse?

Ligases are the group of enzymes that catalyse the transfer of a group from one kind of molecule to another. These are also called transferases.

 32.Nh2-ch2-cooh Belongs To What Structure?

its the structure of amino acid glaycen

33.Mention The Factors Affecting Solubility Of Compounds?

temperature, pH, structure of compound i.e., whether the compd is straight chain or branched & molecular weight of compd.

34.What Are Geometrical Isomerism? Explain Them With An Example?

Geometrical isomerism is an example of stereo-isomerism. 

This occurs when substances have the same molecular formula, but a different arrangment of their atoms in space. There are three ways that this can happen: 

where there is a C=C bond in the molecule; 

where a molecule has rings; or 

where there is a >C=N bond.

 35.How 'salting Out' Process Is Used In Extraction?

Proteins are precipitated from aqueous solution by high concentrations of neutral salts. This is the"salting -out" process.

Divalent and trivalent ions are more effective than univalent ions.

The salts commonly used for this purpose are NA2SO4,(NH4) 2SO4 Magnesium salts, and phosphates.

36.What Is Saponification Of Oils?

When fats are hydrolysed with alkhali,the free fatty acids react with alkali to form metallic acids.these salts are soaps and this process is called saponification.

37.What Is Redox Potential Of An Organic Compound?

The quantitative measure of the affinity of a compound to lose or gain electrons is the redox potential.

38.What Is Lithipone?

Lithipone is a white pigment.it is amixture of BaSO4&ZnS.

39.What Is Difference Between Anti-aromatic And Non-aromatic Compounds?

Anti aromatic compounds follows 4npi electron rule and are cyclic compounds, planar, where as non aromatic are non planar

INORGANIC QUESTIONS

 1.What is grignard Reagent ?

 RM9X

2.Aqua regia is mixture of ..

 Hydrochloric acid and nitric acid (3:1)

3.Name the heaviest natural occurring element in periodic table.

Uranium

4.How much oxygen is present in our atmosphere?

21% oxygen 78% nitrogen 1%other gases

5.What is the name of hydrochloric acid ?

Muriatic acid

6.Litmus paper used in laboratory is obtained from

Lichen

7.Which gas is also called as the laughing gas ?

 Nitrous oxide (N20)

8.What is chemical name of bleaching powder

Calcium hypochloride [Ca(CIO)2]

9.What element is also called as a quick silver ?

Mercury

10.What is chemical name of baking soda ?

Sodium bicarbonate (NaHCO3)

11.Which of the gas is present in under pressure in soft drinks ?

Carbon dioxide (CO2)

12.Galvanized iron is made up by coating and with ?

Zinc

13.Which of the following gas is mainly present in LPG & CNG

LPG –Butane, CNG – Methane CHEM

14.What is Normality ?

Normality is difined as the number of equivalent weight of solute dissolve in one liter solution.

15. What is Molality ?

Molality is defined as the number of moles of solute per kilogram of solvent.

16.What is Molarity ?

Molarity is defined as the number of moles of solute per liter in solution.

17.Which metal is heaviest ?

Osmium

18.Hydrogen gas is not feasible in atmosphere because.

It is lighter than air it can easily escape from earth gravity

19.Solder is an alloy of which substance

Tin and lead

20.Hydrogen bomb is based on principle of..

Nuclear fusion

21.Most abundant metal in Earth crust is ?

Aluminium

22.Alum is mainly used as a….

Purifier for water

23.Chemical name of washing soda

Sodium carbonate ( NaCO3)

24.During the process of rusting the weight of iron is..

Increase

25.Cobalt is found which vitamin ?

Vitamin B12

26.Aluminium metal is extracted from which ore

 Bauxite.

27.Which element is used to prepare fireproof and waterproof clothes?

Calcium hydride (CaH2)

28.Which material is used in making of safety matches?

Red phosphorus

29.which catalyst is used for the synthesis of sulfuric acid by contact process.

Platinum

30.Which gas is used in filling electric bulbs ?

Argon

31.Give some examples of oxidizing agents.

KMN04,K2Cr207, H2O2.

32.Give some examples of Reducing agent.

LIAIH4, NABH4,KI

33.What is PK data :- PK describes a drug’s exposure by characterizing absorption, distribution, bioavailability, metabolism, and excretion as a function of time. PD describes drug response in terms of biochemical or molecular interactions.

INTERVIEW QUESTIONS ON HPLC INSTRUMENT

Q1) What are the parameter of HPLC calibration?

Flow rate accuracy (pump Module) Injector accuracy Carry over System precision Wavelength accuracy Injector linearity Detector linearity Gradient performance check Column oven temperature .

Q2) What is integration in HPLC?

Chromatographic peak integration defines an operation on which the area under the chromatographic peak is measured. The measurement is based on the integral technique of splitting the peak into a large number of rectangles, which are then summed to provide an estimate of the total area under the peak.

There are some integration parameter

1) Minimum area 2) Tailing 3) Fronting etc…

Q3) What is SST in HPLC?

 SST is commonly used to verify resolution, column efficiency, and repeatability of a chromatographic system to ensure its adequacy for a particular analysis. According to the United States Pharmacopeia (USP) and the International Conference on Harmonization (ICH), SST is an integral part of many analytical procedures.

Q3) What is degassing in HPLC?

Degassing is the term used to describe dissolved gases coming out of solution. This phenomenon can also occur in a HPLC system where rough surfaces produce nucleation sites for bubble formation. … In HPLC analysis the problems produced by bubble formation can largely be prevented, by degassing the mobile phase.

Q4) What is RRF value in HPLC?

 Relative Response Factor (RRF) is an alternate method for the determination of the quantity of the impurities present in pharmaceutical products and amount of the impurity can be calculated with the help of peak area of the components.

Q5) What is resolution in HPLC ?

Resolution. The resolution of a elution is a quantitative measure of how well two elution peaks can be differentiated in a chromatographic separation. It is defined as the difference in retention times between the two peaks, divided by the combined widths of the elution peaks.

Q6) What is needle wash in HPLC?

The needle in the HPLC system is used to introduce the sample into the mobile phase so that it can be separated on the HPLC column. The needle wash is used to clean the needle after an injection.

Q7) What is USP tailing factor?

The tailing factor is a measure of peak tailing. It is defined as the distance from the front slope of the peak to the back slope divided by twice the distance from the center line of the peak to the front slope, with all measurements made at 5% of the maximum peak height.

Q8) What is RT and RRT in HPLC?

 The amount of time it takes for the compound to pass through the column is the retention time (RT). The relative retention time (RRT) is the comparison of the RT of one compound to another.

Q9) Why do we get negative peaks in HPLC ?

 A negative peak means that there is less absorbance while the peak is passing through the detector than when the mobile phase is passing through. It is likely due to the mobile phase has more absorbance than the analyte at the monitored wavelength.

Q10) What are the advantages of HPLC?

 Speed, Efficiency and Accuracy. Compared to other chromatographic techniques, such as TLC, HPLC is extremely quick and efficient. It uses a pump, rather than gravity, to force a liquid solvent through a solid adsorbent material, with different chemical components separating out as they move at different speeds.

Q11) What is retention time?

The time taken by the analyte peak to reach the detector after sample injection.

Q12) What is stationary phase in HPLC?

The packing material of the column, which is the immobile phase involved in the chromatographic process. · Column used as a stationary phase.

Q13) What is mobile phase in HPLC?

Mobile phase: The liquid that moves the solute through column.

Q14) On the basis of modes & On the basis of elution technique HPLC are how many types?

 – Based on modes of chromatography

> Normal phase mode

 > Revesre phase mode.

 Based on elution technique

> Isocratic separation

 > Gradient separation

Q15) what is HPLC?

 High-performance liquid chromatography (HPLC) is an analytical technique to separate, identify, and quantify components in a mixture. It is the single biggest chromatography technique essential to most laboratories worldwide.

Most Common Interview Questions

1.What are your strengths?

2.What are your weaknesses?

3.Why are you interested in working for [insert company name here]?

4.Where do you see yourself in five years? Ten years?

5.Why do you want to leave your current company?

6.Why was there a gap in your employment between [insert date] and [insert date]?

7.What can you offer us that someone else can not?

8.What are three things your former manager would like you to improve on?

9.Are you willing to relocate?

10.Are you willing to travel? *(Post COVID-19)

11.Tell me about an accomplishment you are most proud of.

12.Tell me about a time you made a mistake.

13.What is your dream job?

14.How did you hear about this position?

15.What would you look to accomplish in the first 30 days/60 days/90 days on the job?

16.Discuss your resume.

17.Discuss your educational background.

18.Describe yourself.

19.Tell me how you handled a difficult situation.

20.Why should we hire you?

21.Why are you looking for a new job?

22.Would you work holidays/weekends?

23.How would you deal with an angry or irate customer?

24.What are your salary requirements? (Hint: if you’re not sure what constitutes a fair salary range and compensation package, research the job title and/or company on Glassdoor.)

25.Give a time when you went above and beyond the requirements for a project.

26.Who are our competitors?

27.What was your biggest failure?

28.What motivates you?

29.What’s your availability?

30.Who’s your mentor?

31.Tell me about a time when you disagreed with your boss.

32.How do you handle pressure?

33.What is the name of our CEO?

34.What are your career goals?

35.What gets you up in the morning?

36.What would your direct reports say about you?

37.What were your bosses’ strengths/weaknesses?

38.If I called your boss right now and asked him/her what is an area that you could improve on, what would he/she say?

39.Are you a leader or a follower?

40.What was the last book you’ve read for fun?

41.What are your co-worker pet peeves?

42.What are your hobbies?

43.What is your favorite website?

44.What makes you uncomfortable?

45.What are some of your leadership experiences?

46.How would you fire someone?

47.What do you like the most and least about working in this industry?

48.Would you work 40+ hours a week?

49.What questions haven’t I asked you?

50.What questions do you have for me?